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目的观察苯磺酸氨氯地平联合贝那普利治疗单纯收缩期高血压的疗效。方法随机将150例单纯收缩期高血压患者分为3组,A组50例,口服苯磺酸氨氯地平5.0mg/d;B组50例,口服贝那普利10mg/d;C组50例,口服苯磺酸氨氯地平5mg+贝那普利10mg,1次/d,疗程4周,对比分析3组的疗效。结果 A组、B组与治疗前相比,A组、B组总有效率收缩压下降差异有统计学意义(P<0.05);控制收缩压,苯磺酸氨氯地平联合贝那普利疗效明显大于单纯苯磺酸氨氯地平和贝那普利组(P<0.05)。结论苯磺酸氨氯地平联合贝那普利治疗单纯收缩期高血压的疗效优于单种用药,安全性好。
Objective To observe the efficacy of amlodipine besylate combined with benazepril in the treatment of isolated systolic hypertension. Methods A total of 150 patients with isolated systolic hypertension were randomly divided into three groups: group A, 50 patients, oral administration of amlodipine besylate 5.0mg / d; group B, 50 patients, oral benazepril 10mg / d; group C, 50 For example, oral administration of amlodipine besylate 5mg + benazepril 10mg, 1 / d, course of treatment for 4 weeks, comparative analysis of the efficacy of the three groups. Results Compared with those before treatment, the total effective systolic blood pressure in group A and group B decreased significantly (P <0.05). Controlled systolic blood pressure, the effect of amlodipine besylate combined with benazepril Significantly greater than the simple amlodipine besylate and benazepril group (P <0.05). Conclusion The efficacy of amlodipine besylate combined with benazepril in the treatment of isolated systolic hypertension is better than that of single drug, which has good safety.