目的　探讨高渗盐水在低钠性顽固性心力衰竭治疗过程中的作用和可能出现的并发症以及防治对策。方法　分析 3%高渗盐水治疗低钠性顽固性心力衰竭前后的电解质、尿素氮、肌酐、心率、血压、心功能的变化。结果　治疗前后心功能、电介质、尿素氮、肌酐有明显改善 ,血压轻度升高 ,心率无明显变化。结论　高渗盐水能快速有效地纠正低钠血症 ,有助于心功能的迅速改善 ,降低血尿素氮、肌酐。对血压和心率影响不大。 Objective To investigate the role of hypertonic saline in the treatment of patients with low sodium refractory heart failure and possible complications and prevention and treatment measures. Methods The changes of electrolytes, urea nitrogen, creatinine, heart rate, blood pressure and heart function in 3% hypertonic saline before and after treatment for patients with low sodium content refractory heart failure were analyzed. Results Before and after treatment, heart function, electrolyte, urea nitrogen, creatinine were significantly improved, mild increase in blood pressure, no significant change in heart rate. Conclusion Hypertonic saline can quickly and effectively correct hyponatremia, which can help improve the cardiac function rapidly and decrease blood urea nitrogen and creatinine. Little effect on blood pressure and heart rate.