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目的 通过比较妊娠哺乳期乳腺癌与非妊娠哺乳期乳腺癌的临床特点以及预后,探讨妊娠哺乳期乳腺癌的临床特点与治疗.方法 比较新疆医科大学附属肿瘤医院2001-2008年间22例妊娠哺乳期乳腺癌患者和60例非妊娠哺乳期乳腺癌患者(<45岁)的临床病理学特征、复发转移及生存情况.结果 妊娠哺乳期乳腺癌与非妊娠哺乳期乳腺癌5年无病生存率分别为78%以及81%,差异无统计学意义(P>005);相对于非妊娠哺乳期乳腺癌患者,妊娠哺乳期乳腺癌患者的发病时间较长,分期相对较晚,其病理类型,受体情况差异无统计学意义(P>005).结论 妊娠、哺乳并不是乳腺癌的不良预后指标,对于妊娠哺乳期乳腺癌患者应制定个体化、综合治疗方案.
Objective To compare the clinical features and prognosis of breast cancer in lactating and non-pregnant breast-feeding during pregnancy, and to explore the clinical features and treatment of breast-feeding during pregnancy and lactation.Methods 22 cases of pregnancy and lactation in Cancer Hospital Affiliated to Xinjiang Medical University from 2001 to 2008 Breast cancer patients and 60 non-pregnant breast-feeding breast cancer patients (<45 years old) .Results The 5-year disease-free survival rates of breast-feeding breast-feeding and non-lactating breast cancer were Compared with 78% and 81%, respectively, with no significant difference (P> 005). Compared with non-pregnant breast-feeding breast cancer patients, breast cancer in pregnancy and lactation had a longer onset time and relatively late stage. The pathological type, (P> 005) .Conclusion Pregnancy and lactation are not the indicators of poor prognosis for breast cancer, and should be formulated as individualized and comprehensive treatment for breast-cancer patients during pregnancy and lactation.