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目的临床药师通过参与1例视网膜母细胞瘤(retinoblastoma,RB)患儿多次全身化疗的药学实践,探讨儿童化疗远期安全性的药学监护。方法临床药师根据患儿的实际情况,提供咨询意见和药学信息支持,梳理多次全身化疗的远期毒性,并进行全程药学监护。结果患儿顺利完成本次化疗,并接受建议前往寻求外科干预。结论多次全身化疗相关远期毒性可显著影响RB患儿生活质量,临床药师应加以关注和监护。
Objective To investigate the pharmacological protection of long-term chemotherapy for pediatric chemotherapy by participating in the pharmacy practice of multiple systemic chemotherapy in one patient with retinoblastoma (RB). Methods Based on the actual situation of children, clinical pharmacists provided advice and pharmacy information support, combed the long-term toxicity of multiple systemic chemotherapy and carried out full-scale pharmacy care. Results The successful completion of this chemotherapy in children, and accept the recommendations to seek surgical intervention. Conclusion Multiple systemic chemotherapy-related long-term toxicity can significantly affect the quality of life of children with RB, clinical pharmacists should pay attention and custody.