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在泰国东北部的耐氯喹啉恶性疟流行区对84例15岁以上的恶性疟患者的治疗问题作了研究。患者随机分为2组,分别用奎宁-甲氟喹啉或奎宁-乙胺嘧啶-周效磺胺治疗。奎宁剂量,每次540毫克基质,每12小时服1次。若病情严重则用双盐酸奎宁,成人490毫克基质加入0.9％氯化钠500毫升中,静滴4小时以上。研究期间,每8小时测静脉或毛细血管血中疟原
The treatment of 84 cases of falciparum malaria in patients over the age of 15 years in the endemic area of northeastern Thailand resistant to chloroquine falciparum malaria was studied. Patients were randomly divided into two groups, respectively quinine - mefloquine quinine or quinine - pyrimethamine - psoxamide treatment. Quinine dose of 540 mg per substrate, once every 12 hours. If the disease is serious with quinine dihydrochloride, 490 mg of adult matrix added 0.9% sodium chloride 500 ml, intravenous infusion of more than 4 hours. During the study, venous or capillary blood malaria was measured every 8 hours