论文部分内容阅读
目的:观察痰热清辅助治疗再生障碍性贫血合并肺部感染的疗效及其安全性。方法:将53例再生障碍性贫血合并肺部感染患者随机分为治疗组(n=27例)与对照组(n=26例),对照组单用敏感抗生素治疗,治疗组在抗生素治疗的基础上加用痰热清注射液治疗。两组疗程均为2周,比较两组临床疗效和细菌学变化,以及体温恢复正常时间、咳嗽咳痰消失时间、肺部啰音消失时间和X线胸片恢复时间等情况,同时观察两组的不良反应。结果:治疗组治疗总有效率为85.2%,对照组为69.2%,差异有统计学意义(P<0.05)。治疗组体温恢复正常时间、咳嗽咳痰消失时间、啰音消失时间及X线胸片恢复时间与对照组比较,均明显缩短(P<0.05)。治疗组细菌消除数明显高于对照组(P<0.05)。两组治疗过程中未见严重不良反应。结论:痰热清辅助治疗再生障碍性贫血合并肺部感染疗效显著,不良反应少,值得临床推广应用。
Objective: To observe the Tanreqing adjuvant treatment of aplastic anemia complicated with pulmonary infection efficacy and safety. Methods: A total of 53 patients with aplastic anemia complicated with pulmonary infection were randomly divided into treatment group (n = 27) and control group (n = 26). The control group was treated with sensitive antibiotics alone. The treatment group was treated with antibiotics Add Tanreqing injection on the treatment. Two courses of treatment were 2 weeks, the clinical efficacy and bacteriological changes were compared between the two groups, as well as the normal temperature recovery time, the disappearance of cough and sputum time, pulmonary rales disappeared time and X-ray recovery time, etc., while two groups Adverse reactions. Results: The total effective rate was 85.2% in the treatment group and 69.2% in the control group, the difference was statistically significant (P <0.05). The body temperature recovery time, cough and expectoration disappear time, rales disappear time and X-ray chest recovery time compared with the control group, were significantly shorter (P <0.05). The number of bacteria in the treatment group was significantly higher than that in the control group (P <0.05). No serious adverse reactions were observed during the two groups. Conclusion: Tanreqing adjuvant treatment of aplastic anemia complicated with lung infection has significant curative effect and few adverse reactions, which is worthy of clinical application.