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反复自然流产(recurrent spontaneous abortion,RSA)是指连续发生2次或2次以上的自然流产,流产常发生在同一妊娠月份,约占妊娠总数1%~3%[1]。近年来,基础免疫学及免疫遗传学研究有了飞速发展,越来越多的资料证明,免疫异常确实为RSA的重要原因之一,40%的RSA与免疫异常有关,以早孕流产较多见。为探讨细胞因子免疫平衡状态对RSA的影响及其发生机制,对RSA患者检测部分细胞因子水平并分析了细胞因子免疫平衡状态,现报
Recurrent spontaneous abortion (RSA) refers to two or more consecutive spontaneous abortion, abortion often occurs in the same month of pregnancy, accounting for about 1% to 3% of the total number of pregnancies [1]. In recent years, the basic immunology and immune genetics research has been rapid development, more and more data show that immune abnormalities indeed one of the important reasons for RSA, 40% of the RSA and immune abnormalities related to early pregnancy miscarriage more common . To investigate the impact of cytokine immune balance status on RSA and its mechanism, some cytokine levels in RSA patients were assayed and cytokine immune balance status was analyzed