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目的探讨幽门螺旋杆菌(Helicobaterpyloi,Hp)与高原红细胞增多症(highaltitudepolycythemia,HAPC)合并消化性溃疡的临床特点。方法5.5年中对5203例病人进行上消化道内镜检查,检出HAPC合并消化性溃疡49例(0.94%)。男性44例,女性5例(8.81,P<0.001)。Hp检测采用改良cimtnz染色液染色,凡一处阳性者均按阳性统计。结果49例HAPC患者共查出溃疡71处,溃疡面积直径>1.5cm28处(39.4%),>2.0cm4处(5.6%),其中胃多发性溃疡占24.5%,十二指肠溃疡占20.4%,复合性溃疡占20.4%,胃角溃疡占16.3%。Hp感染率高达89.9%。结论HAPC合并消化性溃疡男性多于女性;职业以体力劳动患病率高;汉族为主,临床症状除上腹痛外,其它症状不典型,上消化道出血是其主要并发症。溃疡面大、溃疡深凹苔厚、愈合慢、易复发的临床特征。探讨Hp感染与HAPC合并消化性溃疡为其发病机制和规律,具有重要意义。
Objective To investigate the clinical features of Helicobaterpyloi (Hp) combined with highhalter polycythemia (HAPC) complicated with peptic ulcer. Methods 5203 patients underwent upper gastrointestinal endoscopy in 5.5 years, and 49 cases (0.94%) of HAPC complicated with peptic ulcer were detected. There were 44 males and 5 females (8.81, P <0.001). Hp detection using improved cimtnz stain staining, where a positive were positive statistics. Results A total of 71 ulcers were found in 49 patients with HAPC. The ulcer area was> 1.5cm28 in diameter (39.4%) and> 2.0cm4 (5.6%), of which gastric ulcer was 24.5% and duodenal ulcer was 20.4% , Complex ulcer accounted for 20.4%, gastric ulcer accounted for 16.3%. Hp infection rate as high as 89.9%. Conclusions There are more men than women in HAPC complicated with peptic ulcer. The occupational rate is high in manual labor. The majority of Han people are HCPC. The clinical symptoms include atypical abdominal pain, upper gastrointestinal bleeding is the main complication. Large ulcers, deep ulcer thick moss, healing slow, easy to relapse clinical features. To investigate the relationship between Hp infection and HAPC complicated with peptic ulcer is its pathogenesis and regularity, which is of great significance.