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目的了解2015年新疆食源性疾病中诺如病毒的感染状况及基因组型别分布,为食源性疾病中诺如病毒的预防控制提供依据。方法 2015年新疆8家哨点医院的1 033例食源性疾病患者为监测对象,采用实时荧光定量PCR法进行诺如病毒核酸检测。结果 1 033份粪便标本中阳性74份,阳性率为7.16%。发病时间以5月-8月为高峰;8个开展监测的地区中以博州(23.33%)阳性率最高;年龄分布以3岁以下儿童组及20岁以上成人组所占比例较高,分别为39.19%和32.43%,发病人群男、女差异无统计学意义。GⅠ、GⅡ基因组构成比分别为12.16%和85.14%,GⅠ+GⅡ混合感染占2.7%。结论 2015年新疆地区食源性疾病中有近8%的患者是由诺如病毒感染引起,春末至夏季可能为流行高峰,3岁以下儿童和20岁以上成人为重点人群,流行株以GⅡ基因组为主。
Objective To understand the status and distribution of norovirus in food-borne diseases in Xinjiang in 2015, and provide evidence for the prevention and control of norovirus in food-borne diseases. Methods A total of 1033 food-borne disease patients from 8 sentinel hospitals in Xinjiang were enrolled in this study. Norovirus nucleic acid was detected by real-time fluorescence quantitative PCR. Results A total of 74 samples from 1 033 stool samples were positive, with a positive rate of 7.16%. The onset time was the peak in May-August. The highest positive rate was in Bozhou (23.33%) in the 8 districts where monitoring was conducted. The distribution of age was higher in children under 3 and adults over 20, respectively 39.19% and 32.43%, respectively. There was no significant difference in the incidence of male and female patients. The genotypes of GⅠ and GⅡwere 12.16% and 85.14%, respectively, and GⅠ + GⅡ mixed infection accounted for 2.7%. Conclusions In 2015, nearly 8% of food-borne diseases in Xinjiang were caused by Norovirus infection. It may be the peak of epidemic in late spring to summer, and children under 3 years of age and adults over 20 years of age as the key population. The prevalence of GⅡ Genome-based.