论文部分内容阅读
目的:探讨吉西他滨联合奥沙利铂经肝动脉化疗栓塞对肝癌术后复发的预防作用及其疗效分析。方法:回顾性分析2006年1月～2011年10月我院收治入院的97例晚期原发性肝癌患者的临床资料,将患者随机分为观察组(48例)和对照组(49例),观察组采用吉西他滨联合奥沙利铂,对照组采用阿霉素灌注进行肝动脉化疗栓塞治疗,观察两组不同患者对肝癌术后复发的预防作用及其临床疗效。结果:两组患者疾病控制率及1年、2年的生存率比较上差异有统计学意义(P<0.05)。结论:在肝癌治疗中给予吉西他滨联合奥沙利铂经肝动脉化疗栓塞治疗,疗效确切,不良反应较轻,耐受性好,帮助患者改善生活质量,是晚期原发性肝癌的有效治疗方案。
Objective: To investigate the preventive effect of gemcitabine and oxaliplatin combined with transcatheter arterial chemoembolization on postoperative recurrence of hepatocellular carcinoma and its therapeutic effect. Methods: The clinical data of 97 patients with advanced primary hepatocellular carcinoma admitted to our hospital from January 2006 to October 2011 were retrospectively analyzed. The patients were randomly divided into observation group (48 cases) and control group (49 cases) The observation group was treated with gemcitabine combined with oxaliplatin, while the control group was treated with adriamycin infusion for transcatheter arterial chemoembolization. The preventive effect and clinical efficacy of two groups of different patients on postoperative recurrence of liver cancer were observed. Results: The two groups of patients with disease control rate and 1 year, 2 year survival rate difference was statistically significant (P <0.05). Conclusion: Gemcitabine and oxaliplatin given by transcatheter arterial chemoembolization in the treatment of hepatocellular carcinoma are effective and effective in the treatment of advanced primary liver cancer. The curative effect is definite, the adverse reactions are mild, the tolerance is good, and the patients are helped to improve their quality of life.