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肿瘤型人工关节假体的首例应用是1940年Moore等~([1])为1例骨巨细胞瘤患者植入的股骨上端金属假体。直到植入后2年患者因心力衰竭死亡,该假体一直未发生无菌性松动。由于术后复发率高,原发恶性骨肿瘤的保肢治疗在当时并未被广泛接受~([2]),肿瘤型人工关节假体也较少。20世纪下半叶,放化疗的进步为原发骨肉瘤及转移瘤的保肢治疗创造了条件~([3-5])。肿瘤型人工关节假体的应用才逐渐广泛。
The first application of a tumor-type artificial joint prosthesis was performed by Moore et al. ([1]) in 1940 as a femoral upper end metal prosthesis implanted in one patient with giant cell tumor of the bone. The prosthesis never had aseptic loosening until the patient died of heart failure 2 years after implantation. Due to the high rate of postoperative recurrence, limb salvage therapy of primary malignant bone tumors was not widely accepted at the time (2) and there were fewer tumor-type prosthetic joints. The second half of the 20th century, advances in radiotherapy and chemotherapy for the salvage of osteosarcoma and metastatic tumor created the conditions for limb salvage ~ ([3-5]). The application of tumor-type artificial joint prosthesis gradually widened.