论文部分内容阅读
目的探讨加强血糖控制对于改善妊娠期糖尿病患者母体及新生儿妊娠结局的效果。方法选取2013年12月-2015年12月在河源市妇幼保健院进行分娩的临床资料完整的妊娠期糖尿病患者100例,根据患者的血糖控制情况分为血糖控制良好组(对照组,n=52)和血糖控制不良组(观察组,n=48),并且选取同一时期在该院进行分娩的正常孕妇61例作为健康对照组。比较各组孕妇的妊娠结局和新生儿的情况。结果观察组孕妇的各种妊娠母体并发症的发生率显著高于健康对照组(P<0.05),各种母体并发症中,观察组孕妇羊水过多、终止妊娠、产后出血的发生率显著高于对照组孕妇,差异有统计学意义(P<0.05),对照组孕妇只有胎膜早破发生率显著高于健康对照组孕妇(P<0.05),其他并发症的发生率差异无统计学意义(P>0.05)。观察组新生儿的各种新生儿并发症发生率显著高于健康对照组(P<0.05),新生儿Appgar评分方面,观察组显著低于对照组(P<0.05),对照组又显著低于健康对照组(P<0.05),差异均有统计学意义。结论强化对妊娠期糖尿病孕妇加强血糖控制,能够有效降低妊娠期糖尿病患者的母体并发症和新生儿并发症的发生率,从而改善妊娠结局。
Objective To explore the effect of enhancing glycemic control on pregnancy outcomes in maternal and newborn infants with gestational diabetes mellitus. Methods A total of 100 cases of gestational diabetes mellitus with clinical data from December 2013 to December 2015 in Heyuan MCH were selected and divided into two groups according to their glycemic control: control group (n = 52) ) And poor glycemic control group (observation group, n = 48), and selected the same period in the hospital for delivery of 61 normal pregnant women as a healthy control group. Pregnancy outcomes and newborns in each group were compared. Results The incidence of various maternal complications in pregnant women in observation group was significantly higher than that in healthy controls (P <0.05). In all kinds of maternal complications, the incidence of polyhydramnios, termination of pregnancy and postpartum hemorrhage in observation group were significantly higher (P <0.05). The incidence of premature rupture of membranes in pregnant women in the control group was significantly higher than that in healthy pregnant women (P <0.05), while the incidence of other complications was not statistically significant (P> 0.05). The incidence of neonatal complications in the observation group was significantly higher than that in the healthy control group (P <0.05). In the neonatal Appgar score, the observation group was significantly lower than the control group (P <0.05), and the control group was significantly lower than Healthy control group (P <0.05), the differences were statistically significant. CONCLUSIONS: Intensification of glycemic control in pregnant women with gestational diabetes mellitus can reduce the incidence of maternal complications and neonatal complications in gestational diabetes mellitus patients and thus improve pregnancy outcome.