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观察了怀牛膝皂甙A对动物子宫平滑肌的作用。结果发现：给药后子宫收缩幅度增高，频率加快，张力增加，子宫收缩曲线下面积亦显著增加，并呈一定的浓度依赖关系。在0．12g／L浓度时，对不同生理状态下的大鼠离体子宫均有明显兴奋作用，但对幼龄子宫作用最弱，对晚孕子宫作用最强；对大鼠宫角平滑肌有明显兴奋作用，对宫颈兴奋作用不明显。在体家兔子宫实验发现，局部分别给子0．069／L、0．129／L及0．249／L的怀牛膝皂甙A均有明显兴奋未孕及已孕家兔在体子宫的作用。
The effect of Achyranthes bidentata A on animal uterine smooth muscle was observed. The results showed that: After the administration, the uterine contraction amplitude increased, the frequency increased, the tension increased, and the area under the uterine contraction curve also increased significantly, and showed a certain concentration-dependent relationship. At the concentration of 0.12g/L, there was obvious excitatory effect on rat uterus under different physiological conditions, but it had the weakest effect on young uterus and the strongest effect on uterus of late pregnancy. Obviously excited, no obvious effect on the cervix excitement. In the Rabbit House experiment, it was found that 0.069/L, 0.129/L, and 0.249/L of Achyranthes bidentata A were partially excitable and were not gestating in the uterus. effect.