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酪氨酸酶是一种多酚氧化酶,是昆虫换羽期的一种重要的酶,寻找它的抑制剂可以作为寻找杀虫剂的一种新思路。此外酪氨酸酶抑制剂也广泛用于与色素沉着过多有关的美容和医疗产品中。作者希望从植物中找到酪氨酸酶的抑制剂,结果发现人参叶的甲醇提取物对由酪氨酸酶催化的L-多巴的氧化有抑制活性。
Tyrosinase is a polyphenol oxidase, which is an important enzyme for insects in the molting period. Looking for its inhibitors can be used as a new way of looking for insecticides. Tyrosinase inhibitors are also widely used in cosmetic and medical products related to hyperpigmentation. The authors hope to find tyrosinase inhibitors from plants and found that the methanol extract of ginseng leaves has inhibitory activity against tyrosinase-catalyzed oxidation of L-dopa.