论文部分内容阅读
暴发性脑膜炎球菌感染可在数小时内导致败血症或死亡.脑膜炎球菌脂多糖(LPS,内毒素)通过激活补体系统以及刺激细胞因子释放引起组织损伤,细胞因子的血浓度与发生败血性休克密切相关.血液中补体终末成分(terminal complement component,TCC)缺乏病人对脑膜炎球菌的易感性增加,但是与免疫功能正常者比较,这些病人感染脑膜炎球菌时病死率较低.文章对一名C6缺乏罹患脑膜炎球菌败血症的病人使用新鲜冷冻血浆治疗进行了研究.病人为29岁黑人妇女,血及脑脊液中均
Outbreaks of meningococcal infection can lead to sepsis or death within hours.Millera meningococcal lipopolysaccharide (LPS, endotoxin) causes tissue damage by activating the complement system and stimulating the release of cytokines, and the blood levels of cytokines are associated with septic shock Is closely related to the poor complement of the terminal complement component (TCC) in patients with increased susceptibility to meningococcal disease, but compared with normal immune function, these patients died of meningococcal mortality was low. Patients with a C6-deficient meningococcal septicemia were studied using fresh frozen plasma therapy, a 29-year-old black woman with blood and cerebrospinal fluid