近十年来,认为输血能增加头颈部癌复发的报道有三篇,其中二篇并没有采用多因素分析法,另一篇虽采用了多因素分析,但没有包括肿瘤切除安全缘这一因素。最近Robbins等采用多因素分析法,结果表明输血与感染并发症无明显联系。对从旧金山区5个医疗中心的640例连续病例中严格筛选出1981～1987年的104例头颈鳞癌患者进行调查,平均随访期为3年,其中男77例,女27例,平均年龄62岁,喉部癌占36%、口腔癌占34%、咽部癌及鼻窦癌分别占27%及4%,属临床Ⅱ期34%、Ⅲ期41%、Ⅳ期25%。这些病例均为术前活检证实、均首先采用手术、术前未行放疗及化疗、肿块 Over the past decade, there have been three reports that transfusion of blood can increase the recurrence of head and neck cancer. Two of them did not use multivariate analysis and the other did not include the factor of safety of tumor resection. Recently Robbins and other multivariate analysis, the results showed no significant correlation between blood transfusion and infection complications. A total of 104 cases of head and neck squamous cell carcinoma were screened from 640 consecutive cases in 5 medical centers in San Francisco for a period of 3 years. There were 77 males and 27 females, with an average age of 62 Thirty-six years old, throat cancer accounted for 36%, oral cancer 34%, pharyngeal cancer and sinus cancer accounted for 27% and 4%, respectively, 34% of clinical stage Ⅱ, Ⅲ 41%, Ⅳ 25%. These cases were confirmed by preoperative biopsy, are the first to use surgery, preoperative radiotherapy and chemotherapy, lumps