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目的分析克拉霉素联合替硝唑治疗小儿幽门螺杆菌(Hp)相关性胃炎的疗效。方法 80例幽门螺杆菌相关性胃炎患儿,按照数字随机方式分为对照组和实验组,每组40例。对照组患儿采用阿莫西林联合甲硝唑治疗,实验组患儿采用克拉霉素联合替硝唑治疗。比较两组的治疗效果。结果实验组临床治疗总有效率95.0%高于对照组80.0%,差异具有统计学意义(P<0.05)。实验组并发症发生率2.5%与对照组5.0%比较差异无统计学意义(P>0.05)。结论在对小儿幽门螺杆菌相关性胃炎进行治疗时,克拉霉素联合替硝唑治疗具有比较显著的临床效果,而且安全可靠,具有临床应用价值。
Objective To analyze the curative effect of clarithromycin combined with tinidazole in the treatment of Helicobacter pylori (Hp) -related gastritis in children. Methods Eighty children with Helicobacter pylori-associated gastritis were randomly divided into control group and experimental group, 40 cases in each group. Children in the control group were treated with amoxicillin combined with metronidazole. Children in the experimental group were treated with clarithromycin plus tinidazole. Compare the treatment effect of two groups. Results The total effective rate of clinical trial in experimental group was 95.0% higher than that in control group (80.0%), the difference was statistically significant (P <0.05). The incidence of complications in experimental group was 2.5% compared with 5.0% in control group, but there was no significant difference (P> 0.05). Conclusion In the treatment of Helicobacter pylori-associated gastritis in children, clarithromycin combined with tinidazole has a significant clinical effect, and is safe and reliable, and has clinical value.