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目的:探讨内放射治疗对胶质瘤引起的癫痫的影响。方法:回顾性分析2004年后利用I131内放射治疗的成人幕上恶性脑胶质瘤合并有癫痫发作的患者23例,统计其在治疗前1月及治疗后1月、2月时的癫痫发作频率和类型,并分析肿瘤体积变化与发作频率变化的关系。结果:治疗后1月癫痫发作无明显改变,治疗后2个月癫痫发作明显减少,13例无癫痫发作,另外10例有发作患者频率也明显下降,其中肿瘤缩小超过1/2者78%无癫痫发作。结论:I131内放射治疗的成人幕上恶性脑胶质瘤可以明显减少患者的癫痫发作。
Objective: To investigate the effect of intra-radiotherapy on epilepsy induced by glioma. Methods: A retrospective analysis of 23 patients with malignant glioma of supratentorial supratentorial malignant meningioma complicated with intracerebral hemorrhage after I131 treatment in 2004 was conducted. Twenty-three patients with epileptic seizures were observed before January, January and February after treatment Frequency and type, and analyze the relationship between tumor volume changes and seizure frequency changes. Results: There was no significant change in epileptic seizures after 1 month of treatment. Seizure decreased significantly in 2 months after treatment. Thirteen patients had no seizures. The frequency of seizures in the other 10 patients also decreased significantly, of which 78% Seizures. CONCLUSIONS: Adult supratentorial malignant gliomas treated with intra-I131 radiation can significantly reduce seizures in patients.