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目的 探讨非功能胰岛细胞瘤的诊断和治疗方法。 方法 对 7例非功能胰岛细胞瘤患者的临床资料进行回顾性分析。 结果 肿瘤位于胰头部 3例 ,胰体部 2例 ,胰尾部 2例。胰十二指肠切除术 3例 ,胰体胃切除 +脾切除 3例 ,局部切除1例。病理证实恶性 4例 ,良性 3例 ,其中 4例行免疫电镜检查。 7例全部一期治愈出院。 结论 体症、B超、CT是发现本病的主要手段 ,将病理学检查和肿瘤生物学行为结合起来判定良恶性 ,手术切除肿瘤是治疗本病的有效方法。
Objective To investigate the diagnosis and treatment of non-functional islet cell tumor. Methods The clinical data of 7 patients with non-functioning islet cell tumor were analyzed retrospectively. Results The tumor was located in the head of pancreas in 3 cases, pancreatic body in 2 cases and pancreatic tail in 2 cases. Pancreaticoduodenectomy in 3 cases, pancreatic body gastrectomy + splenectomy in 3 cases, partial resection in 1 case. Pathological confirmed malignant in 4 cases, benign in 3 cases, of which 4 cases were immunoelectron microscopy. All seven cases were cured. Conclusion Body disease, B-ultrasound and CT are the main means to discover this disease. Combined with pathological examination and tumor biological behavior, benign and malignant tumors are identified. Surgical resection of tumor is an effective way to treat this disease.