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目的:探讨阿奇霉素与左氧氟沙星联合治疗社区获得性肺炎的临床效果。方法:选择我院2009年11月～2011年11月社区获得性肺炎患者80例,上述患者分为观察组和对照组。2组患者均给予镇咳化痰治疗,给予退热、吸氧及雾化吸入等治疗。对照组患者给予阿奇霉素每天0.5g,每天1次,静脉滴注,连续应用3天后改为口服阿奇霉素,每天0.125g,每天1次。观察组患者给予阿奇霉素和左氧氟沙星,阿奇霉素用法同对照组,左氧氟沙星静脉滴注,每天0.5g,每天1次。2组患者疗程为7～14天。记录2组患者发热消退时间、肺罗音消退时间、血常规恢复正常时间、肺部X线恢复时间。结果:2组患者总有效率比较,差异有统计学意义(P<0.05);观察组发热消退时间、肺罗音消退时间、血常规恢复正常时间、肺部X线恢复时间显著短于对照组,差异有统计学意义(P<0.05)。结论:阿奇霉素与左氧氟沙星联合治疗社区获得性肺炎临床效果显著,值得借鉴。
Objective: To investigate the clinical effect of azithromycin combined with levofloxacin in the treatment of community-acquired pneumonia. Methods: Eighty patients with community-acquired pneumonia were selected from November 2009 to November 2011 in our hospital. The patients were divided into observation group and control group. Both groups were given antitussive phlegm treatment, giving fever, oxygen and inhalation therapy. Patients in the control group were treated with azithromycin 0.5g daily, once daily, by intravenous drip. After three consecutive days of application, oral azithromycin was administered orally at 0.125g daily for 1 day. Patients in the observation group were given azithromycin and levofloxacin, azithromycin use the same control group, levofloxacin intravenous infusion, 0.5g daily, 1 day. 2 groups of patients for 7 to 14 days course of treatment. Two groups of patients were recorded fever subsidence time, lung rales subsided time, blood routine recovery time, pulmonary X-ray recovery time. Results: The total effective rate in the two groups was statistically significant (P <0.05). The fever subsided time, the pulmonary rales subsidence time, the normal time of blood routine recovery, and the pulmonary X-ray recovery time in the observation group were significantly shorter than those in the control group , The difference was statistically significant (P <0.05). Conclusion: Azithromycin combined with levofloxacin in the treatment of community-acquired pneumonia clinical effect is significant, it is worth learning from.