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我院从1986～1993年共收治慢性酒精中毒性神经病20例,其中周围神经病11例,威尼克脑病3例,周围神经病合并威尼克脑病6例,现报告如下.1 临床资料1.1 一般情况 20例均为男性,年龄31～65岁,平均42岁,每日饮酒量0.25～1.00kg,平均400g,持续饮酒3～30年,平均15年.所饮酒均为市售高度白酒.1.2 临床表现 本病多数隐袭起病,少数为亚急性或急性起病.20例患者中,周围性感觉障碍17例,肌肉萎缩2例,有感觉平面3例,病理征阳性3例,癫痫大发作3例,植物神经症状4例,共济失调8例,精神及人格异常10例,计算力及近记忆力下降8例,幻觉7例,虚构4例,眼肌麻痹2例.1.3 辅助检查 本组20例中10例行头颅CT或MRI扫描,8例正常,2例示轻度脑萎缩;6例行脑电图检查.广泛中度异常2例,轻度异常及正常4例,10例行肌电图检查,除1例正常外其余9例均提示神经源性损害.9例威尼克脑病患者智力测定提示不同程度智能障碍.
Our hospital from 1986 to 1993 were treated 20 cases of chronic alcoholic neuropathy, of which 11 cases of peripheral neuropathy, 3 cases of Venenic encephalopathy, peripheral neuropathy with venic encephalopathy in 6 cases are reported as follows.1 Clinical data 1.1 General situation 20 cases All men, aged 31 to 65 years old, with an average of 42 years old, the daily amount of drinking 0.25 to 1.00kg, an average of 400g, continued to drink 3 to 30 years, an average of 15 years of alcohol consumption are commercially available liquor .1.2 Clinical manifestations The majority of insidious onset disease, a small number of subacute or acute onset .20 patients, 17 cases of peripheral sensory disturbances, muscle atrophy in 2 cases, sensory plane in 3 cases, 3 cases of positive pathological signs, epileptic seizures in 3 cases , Autonomic symptoms in 4 cases, ataxia in 8 cases, mental and personality abnormalities in 10 cases, calculating power and memory loss in 8 cases, illusion in 7 cases, fictitious in 4 cases, ocular muscle paralysis in 2 cases.1.3 auxiliary examination in this group of 20 cases In 10 cases of skull CT or MRI scan, 8 cases of normal, 2 cases showed mild brain atrophy; 6 cases of EEG, extensive and moderate abnormalities in 2 cases, mild abnormalities and normal in 4 cases, 10 cases of EMG Except for 1 case of normal, the remaining 9 cases were all suggestive of neurogenic injury, and the intelligence tests of 9 patients with Vicki’s encephalopathy prompted different degrees of intelligence Hinder.