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目的总结两例AIDS相关的口腔上颚卡波西肉瘤(KS)临床诊断治疗经验,了解KS与AIDS的关系,有助于早期诊断和治疗。方法根据病变特点,通过病理组织切片,免疫组化染色以及特殊检查明确诊断口腔上颚KS,对其临床表现,肿瘤特征,治疗方式,疗效进行总结分析。结果两例病例经放疗,抗病毒治疗以及HAART治疗后皮损及口腔病变逐渐好转。结论 KS主要在男性同性恋者中流行,随着HIV通过性传播途径感染的病例不断增加,不排除中原地区发病率增加的可能性,放射治疗对KS是一种安全有效的方法,剂量以40 GY左右为宜,同时给以抗病毒治疗以及HAART治疗,HAART治疗的开始时间与疾病展密切相关。
Objective To summarize the experience of clinical diagnosis and treatment of two AIDS-related oral maxillary Kaposi’s sarcoma (KS) and to understand the relationship between KS and AIDS and to help early diagnosis and treatment. Methods According to the characteristics of the lesions, the maxillary KS was diagnosed by pathological section, immunohistochemical staining and special examination. The clinical manifestations, tumor characteristics, treatment methods and curative effects were summarized. Results After two cases of radiotherapy, antiviral therapy and HAART treatment of skin lesions and oral lesions gradually improved. Conclusions KS mainly prevails in homosexual men. With the increasing number of cases of HIV transmission through sexual transmission, it does not rule out the possibility of increased incidence in the Central Plains. Radiation therapy is a safe and effective method for treating KS with a dose of 40 GY About appropriate, given both antiviral therapy and HAART treatment, HAART treatment start time and disease are closely related.