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目的 :研究淮河水中非挥发性有机物对机体的遗传毒性。方法 :采集淮河源水、自来水厂滤池出水、氯化消毒自来水及大型贮水箱水各 2 0 0升 ,经吸附浓缩后予小鼠灌胃染毒。以胸骨骨髓嗜多染红细胞微核率检测致突变性 ,以精子畸形率检测遗传毒性。结果 :淮河源水及消毒处理过的自来水均有一定程度的致突变及致精子畸形性。遗传毒性大小顺序依次为 :消毒处理过的自来水 >贮水箱水 >源水 >滤池出水。结论 :淮河源水已受到有机诱变物的污染。混凝沉淀具有去除有机物、降低源水遗传毒性作用。而加氯消毒使水质的遗传毒性增高。
Objective: To study the genotoxicity of non-volatile organic compounds in the Huaihe River water to the body. Methods: Collecting water from the Huaihe River, water from the filter plant of the waterworks, disinfecting the tap water and large storage tank water by 200 liters respectively, and injecting and concentrating to the mice for gavage. To sternum bone marrow polychromatic erythrocytes micronucleus rate of detection of mutagenesis, sperm deformity detection genotoxicity. Results: The source water of the Huaihe River and disinfected tap water all had a certain degree of mutagenesis and sperm deformity. Genotoxicity in the order of: disinfection of tap water> storage tank water> source water> filter effluent. Conclusion: The source water of Huaihe River has been contaminated by organic mutagen. Coagulation sediment with removal of organic matter, reduce the source of genotoxic effects of water. However, chlorination disinfection increases the genotoxicity of water.