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目的:编制适用于我国慢性乙肝患者的特异性生活质量量表(QLS-CHB)。方法:采用结构化的决策方法编制条目,对227名患者进行调查后,以反应度分析、相关分析法及因素分析法筛选条目,并对量表进行信、效度的检验。结果:探索性因素分析抽取的四个因子与理论构想的疾病、生理、心理和社会四个维度相符,共解释了总方差的49.635%。条目与各维度的相关为0.531-0.814,各维度与总分的相关为0.697-0.869。QLS-CHB与SF-36总分的相关系数为0.775。总量表的Cronbach’sα系数为0.941,各维度的Cronbach’sα系数为0.775-0.914。总量表的重测相关系数为0.925,各维度的重测相关系数为0.675-0.886。结论:QLS-CHB有良好的信效度。
Objective: To prepare a specific quality of life scale (QLS-CHB) for chronic hepatitis B patients in our country. Methods: The structured decision-making method was used to compile the entries. After investigating 227 patients, the items were screened by reaction analysis, correlation analysis and factor analysis, and the reliability and validity of the questionnaire were checked. Results: The four factors extracted by exploratory factor analysis were consistent with the four dimensions of disease, physiology, psychology and society of the theoretical conception, accounting for 49.635% of the total variance. The correlation between items and each dimension is 0.531-0.814, and the correlation between each dimension and the total score is 0.697-0.869. The correlation coefficient between QLS-CHB and SF-36 score was 0.775. The Cronbach’s α coefficient for the total scale was 0.941 and the Cronbach’s α coefficient for each dimension was 0.775-0.914. The retest correlation coefficient of the total scale is 0.925, and the retest correlation coefficient of each dimension is 0.675-0.886. Conclusion: QLS-CHB has good reliability and validity.