论文部分内容阅读
单基因疾病的致病基因可以成为研究多因素复杂疾病的最佳候选基因.近年来,青少年发病成人型糖尿病(MODY)发病相关基因的单核苷酸多态性(SNP)在导致2型糖尿病(T2DM)遗传易感性增加的现象逐渐被重视.笔者对国内外MODY基因SNP与2型糖尿病相关性研究进行文献综述.“,”Causative genes of monogenic diseases are the best candidate genes to study multifactorial diseases.Previous reports have suggested that variants in the genes for maturity onset diabetes of young (MODY) may increase the risk of type 2 diabetes.In this review,we review the recent association study between MODY genes and type 2 diabetes.