多发性神经病(Polyneuropathy以下简称PN)的的病因是多种多样的。周围性PN综合征的表现是远端肌肉对称性无力,轻触和痛温觉对称性丧失,呈手套样分布,振动觉和位置觉对称性消失,远端比近端更严重,腱反射对称性减弱,以远端更显著。对称性是由于全身性代谢,毒物或炎症病因所致;而肢体最远端部分受损最严重,推测是由于最长的神经纤维对致病因素最敏感。诊断靠病史和神经学检查,主要是靠后者。肌活检、肌电图和肌酶分析有助于PN与原发性肌病的无力相鉴别。本病易与多数性单神经病混淆。在PN综合征 Polyneuropathy (PN) is a variety of causes. Peripheral PN syndrome is characterized by weakness in distal muscular symmetry, loss of sympathetic touch and pain and temperature, glove-like distribution, loss of symmetry of sensation of vibration and position, loss of symmetry of the distal end, and greater symmetry of tendon reflexes Sexually diminished to the more prominent distal. Symmetry is due to systemic metabolism, toxins, or the cause of inflammation; while the most distal limb is most severely damaged, presumably because the longest nerve fibers are the most susceptible to causative agents. Diagnosis by history and neurological examination, mainly by the latter. Muscle biopsy, electromyography and muscle enzyme analysis contribute to PN and primary myopathy inability to distinguish. The disease is easily confused with most mononeuropathies. In PN syndrome