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目的观察分析脑脊液中腺苷脱氨酶水平对结核性脑膜炎的诊断价值。方法将我院2014年5月至2016年5月期间收治的80例脑膜炎患者作为分析对象,根据疾病类型将其分为A组27例(结核性脑膜炎)、B组28例(化脓性脑膜炎)和C组25例(病毒性脑膜炎)。通过酶显色法对三组脑脊液中腺苷脱氨酶水平进行检测,并检测结核性脑膜炎患者治疗后的腺苷脱氨酶水平。结果 B组和C组的腺苷脱氨酶水平均低于A组,组间差异具统计学意义(P<0.05);患者的腺苷脱氨酶水平与治疗时间呈反比,每个时间段之间的差异均具统计学意义(P<0.05)。结论结核性脑膜炎患者可通过腺苷脱氨酶水平准确判断,还可设为临床疗效的监测指标,有较高的诊断价值。
Objective To observe the value of adenosine deaminase in cerebrospinal fluid in the diagnosis of tuberculous meningitis. Methods Eighty meningitis patients admitted from May 2014 to May 2016 in our hospital were divided into group A (27 cases), tuberculous meningitis (group A) and group B (28 cases) Meningitis) and group C 25 cases (viral meningitis). The levels of adenosine deaminase in three groups of cerebrospinal fluid were detected by enzymatic chromogenic method, and the level of adenosine deaminase in patients with tuberculous meningitis was detected. Results The levels of adenosine deaminase in group B and group C were lower than those in group A, the difference was statistically significant (P <0.05). The level of adenosine deaminase in patients was inversely proportional to the treatment time, and each time period The differences were statistically significant (P <0.05). Conclusions Patients with tuberculous meningitis can be accurately judged by the level of adenosine deaminase, but also can be used as monitoring indicators of clinical efficacy, which has high diagnostic value.