通常认为慢性气流阻塞是由气道狭窄或/和产生气流驱动力的肺组织弹性回缩力的丢失所引起。气道病变可分为“大气道”和“小气道”两部分。通过嵌入导管测定不同部位的气道阻力的方法,发现气流阻塞的主要部位是管径小于2～3毫米的终末支气管,即包括最小支气管(管壁有软骨)和细支气管(管壁无软骨的气导气道)二部分,Hogg(1968)称之谓 Chronic airflow obstruction is generally thought to be caused by the narrowing of the airways or / and the loss of elastic recoil force of the lung tissue that produces airflow-driven forces. Airway lesions can be divided into “airways ” and “small airways ” two parts. By embedding catheters in different parts of the airway resistance method and found that the main part of the airflow obstruction is a diameter of less than 2 to 3 mm of the terminal bronchus, that is, including the smallest bronchial (wall with cartilage) and bronchioles (wall without cartilage Of the airway) two parts, Hogg (1968) called the so-called