目的:探讨中药抗菌药物与抑制胃酸分泌药物联用治疗消化性溃疡的临床疗效。方法:将我院收治的64例消化性溃疡患者随机分为对照组和观察组,每组32例,对照组患者单纯应用西医抗菌药及胃酸分泌抑制剂治疗,观察组在此基础上,加用中药抗菌方剂,比较两组患者的治疗效果。结果:观察组患者的治愈率、治疗总有效率均显著高于对照组,P<0.05,差异具有统计学意义;观察组的Hp清除率93.8%(30/32),对照组为75.0%(24/32),组间比较差异有统计学意义(P<0.05)。结论:中药抗菌药物联合抑制胃酸分泌药物治疗消化性溃疡,能有效增强药物抗菌活性,提高治疗效果,值得推广应用。 Objective: To investigate the clinical efficacy of traditional Chinese medicine antibacterial drugs combined with drugs that inhibit gastric acid secretion in the treatment of peptic ulcer. Methods: Sixty-four patients with peptic ulcer admitted to our hospital were randomly divided into control group and observation group, with 32 cases in each group. Patients in the control group were treated with western medicine and gastric acid secretion inhibitor alone. On the basis of this, Anti-bacterial herbs with traditional Chinese medicine, compared the treatment effect of two groups of patients. Results: The cure rate and the total effective rate in the observation group were significantly higher than those in the control group (P <0.05), the difference was statistically significant. The Hp clearance rate in the observation group was 93.8% (30/32) and in the control group 75.0% 24/32). The difference between the two groups was statistically significant (P <0.05). Conclusion: The combination of traditional Chinese medicine antibacterial drugs and gastric acid secretion inhibiting peptic ulcer can effectively enhance the antibacterial activity of the drug and improve the curative effect, so it is worth popularizing and applying.