乙型肝炎(HB)疫苗和BCG能否在婴儿出生时一起免疫,脊髓灰质炎(脊灰)灭活疫苗与HB疫苗同时免疫是否会损害疫苗的应答进行了研究。作者在塞内加尔地区5月龄以内的婴儿中,随机分成3组,A组於出生时接种BCG和首剂HB疫苗,2、3、9月再各接种HB疫苗1剂(5μg/ml);B组的HB疫苗同A组, Whether hepatitis B (HB) vaccine and BCG can be immunized together at birth or not, and whether poliomyelitis (poliomyelitis) inactivated vaccine and HB vaccine simultaneously immunized would compromise the vaccine’s response were investigated. The authors were randomly divided into 3 groups in infants within 5 months of age in Senegal. Group A received BCG and the first dose of HB vaccine at birth, and each received one dose of HB vaccine (5 μg / ml) in February, March and September. B Group HB vaccine with the A group,