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目的：探讨慢性阻塞性肺疾病（ＣＯＰＤ）患者呼吸运动方式和运动受限的原因。方法：ＣＯＰＤ患者在功率自行车上运动至最大运动量，观察其潮气流速容量环的变化特点，并利用相关和逐步回归分析判断运动中最大公斤耗氧量（ＶＯ２ｍａｘ／ｋｇ）与静态最大流速容量环呼气流速间的关系。结果：１ＣＯＰＤ患者运动中潮气流速容量环的变化有其特点；２ＣＯＰＤ患者最大公斤耗氧量与Ｖ７５％、Ｖ５０％和Ｖ２５％呈显著正相关（ｒ分别为０．８５７，０．８７５和０．７８９，Ｐ＜０．０１）；３ＣＯＰＤ患者ＶＯ２ｍａｘ／ｋｇ与Ｖ５０％存在直线回归关系ｔ＝６．３７３，Ｐ＜０．０１。结论：１ＣＯＰＤ患者的特殊呼吸方式为运动中潮气流速容量环逐渐向肺总量位附近偏移；２静态Ｖ５０％减小是ＣＯＰＤ患者运动受限的主要原因。
Objective: To investigate the causes of respiratory movement and exercise limitation in patients with chronic obstructive pulmonary disease (COPD). Methods: The patients with COPD were motored to the maximum amount of exercise on power bicycles and the changes of the capacity ring of the moisture flow were observed. Correlation and stepwise regression analysis were used to determine the maximal oxygen consumption (VO2max / kg) and static maximum flow capacity The relationship between the air flow rate. Results: The changes of volume ring of moisture flow rate in patients with 1COPD had its own characteristics. The maximum oxygen consumption of patients with 2COPD was positively correlated with V75%, V50% and V25% (r = 0.857,0.875 and 0 respectively). 789, P <0.01). There was a linear regression relationship between VO2max / kg and V50% in t = 6.373, P <0.01. CONCLUSIONS: The specific breathing pattern of patients with 1COPD is that the volumetric ring of the tidal flow velocity gradually shifts to the vicinity of the total lung volume during exercise. 2 The decrease of the static V50% is the main reason for the limited exercise in COPD patients.