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本文报道杭州市１９８５～１９８９年市区２２９例初治涂阳肺结核病人，在不住院全程监督或全程管理下，采用２Ｓ３Ｈ３Ｒ３Ｚ３／４Ｈ３Ｒ３（ＤＬ１）和２ＳＨＲＺ／４Ｈ２Ｒ２（ＤＬ１）两种间歇短程化疗（短化）方案治疗。疗程结束痰菌阴转率分别为９７．７％及９９．０％，３年随访复发率为２．４％及３．０％。两方案疗效差异无显著性。认为①６个月间歇短化服药７８～９４次，节省了费用，减少了管理次数值得推广。②原发ＲＦＰ耐药者疗效差，宜改变方案。③全程管理化疗如认真按规范实施，可取得与全程监督管理相似的效果。
This paper reports 229 patients with newly diagnosed smear-positive pulmonary tuberculosis in urban areas from 1985 to 1989 in Hangzhou city. Two kinds of intermittent short-course chemotherapy (DL1) with 2S3H3R3Z3 / 4H3R3 (DL1) and 2SHRZ / 4H2R2 Chemotherapy) program treatment. The sputum negative conversion rate was 97.7% and 99.0% at the end of treatment, and the recurrence rates at 3-year follow-up were 2.4% and 3.0% respectively. No significant difference between the two programs. That ① 6 months intermittent shortening medication 78 to 94 times, saving costs, reducing the number of management worth promoting. ② poor efficacy of primary RFP drug-resistant, should change the program. ③ full management of chemotherapy, such as the serious implementation of the standard, can be obtained with the supervision and management of similar effects.