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目的:探讨2型糖尿病(type 2 diabetes mellitus,T2DM)患者动脉弹性变化及其相关影响因素。方法:选取2013年8月至2015年4月在该院治疗的T2DM患者120例作为观察组,选取我院门诊的健康体检者138例作为对照组,测量人体、实验室及臂踝脉搏波传导速度(Ba PWV)指标。结果:观察组Ba PWV明显高于对照组(P<0.05),Ba PWV与病程、收缩压(SBP)、餐后两小时血糖(2h PG)和甘油三酯(TG)均呈显著正相关(P<0.05或P<0.01)。结论:T2DM患者动脉弹性减弱,相关影响因素包括病程、SBP、2h PG和TG,积极控制血压、血糖和血脂可延缓动脉硬化的发展进程。
Objective: To investigate the changes of arterial elasticity and its related factors in type 2 diabetes mellitus (T2DM) patients. Methods: A total of 120 T2DM patients treated in this hospital from August 2013 to April 2015 were selected as the observation group. 138 healthy volunteers in our hospital were selected as the control group to measure the body, laboratory and brachial-ankle pulse wave conduction Speed (Ba PWV) indicator. Results: The Ba PWV in the observation group was significantly higher than that in the control group (P <0.05). Ba PWV was positively correlated with the duration of disease, systolic blood pressure (SBP), blood glucose (2h PG) and triglyceride (TG) P <0.05 or P <0.01). CONCLUSION: Arterial elasticity is weakened in T2DM patients. The related factors include duration of disease, SBP, 2h PG and TG, and positive control of blood pressure, blood glucose and lipids may delay the development of atherosclerosis.