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胰腺内分泌肿瘤(PETS)的发生率至少占全身内分泌肿瘤的50％以上,且大多数有功能,这是导致一些特殊疾病死亡的主要原因,但由于大多数病人的胰腺内分泌肿瘤为无痛性,且要求避免有关胰岛素依赖性的并发症,目前对胰腺手术的时机和手术范围仍存在着很大的争议。该研究选定了98例多发性内分泌肿瘤病人,其中55例(56％)胰腺内分泌肿瘤,包括女性27例、男性28例,平均年龄37岁,有功能性的35例,无功能性20例。其中38例(64％)完成了胰腺手术,包括4例肿瘤摘除、3例全胰切除、4例Whipple术、27例远端胰腺切除。平均肿瘤大小为2．8 cm。随访发现,第一次手术平均生存7．8年后35例存在复发危险的病人中有7例残存胰腺肿瘤复发,36例无远处转移的手术病人平均生存2．7年后有5例出现远处转移(2例手术时已有远处转移),最终随访结果显示,55例病人中16例死亡,12例带瘤生存,
The incidence of pancreatic endocrine tumors (PETS) accounted for at least 50% of systemic endocrine tumors, and most of them are functional, which is the leading cause of death for some special diseases. However, since pancreatic endocrine tumors are painless in most patients, And asked to avoid complications related to insulin dependence, the current timing and extent of surgery for pancreatic surgery there is still a lot of controversy. The study selected 98 patients with multiple endocrine tumors, of which 55 (56%) pancreatic endocrine tumors, including 27 females, 28 males, mean age 37 years, 35 cases of functional, non-functional 20 cases . Thirty-eight (64%) completed pancreatic surgery, including 4 tumor excisions, 3 total pancreatectomy, 4 Whipple’s surgery and 27 distal pancreatectomy. The average tumor size was 2.8 cm. Follow-up found that the average survival of the first surgery after 7.8 years in 35 patients with the risk of recurrence in 7 patients with recurrent pancreatic cancer recurrence, 36 patients without distant metastasis surgery, the average survival 2.7 months after the emergence of 5 cases Distant metastasis (two cases had distant metastasis at the time of surgery). The final follow-up results showed that 16 of 55 patients died and 12 patients survived with tumor,