视网膜母细胞瘤是罕见病,因而很难估价采用新疗法能否减少正常组织出现的副作用。所以在开始任何临床试验前,都必须进行体内外试验性治疗研究。本文描述了一种视网膜母细胞瘤样肿瘤,能在鼠眼内有规律地生长,且有极高的发生率。经试验证明,其生长特性适于观察眼内治疗反应和进行定量克隆源性测定 Retinoblastoma is a rare disease, so it is difficult to assess whether the introduction of new therapies can reduce the side effects of normal tissue. So before starting any clinical trial, there is a need for in vitro and in vivo experimental treatment studies. This article describes a retinoblastoma-like tumor that grows regularly in the mouse eye and has a very high incidence. The test proved that its growth characteristics are suitable for observing the intraocular therapeutic response and quantitative clonogenic assay