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目的探讨胰岛素与诺和平联用治疗2型糖尿病临床治疗效果。方法选取我院自2011年1月～2013年1月收治的90例2型糖尿病患者,随机分为观察组与参考组各45例,给予观察组患者胰岛素与诺和平联合治疗,给予参考组患者胰岛素注射治疗,观察两组患者治疗前后餐后2h血糖(PBG)、空腹血糖(FBG)、糖化血红蛋白(HbA1c)变化及低血糖发生率。结果两组患者治疗后PBG、FBG、HbA1c均有明显下降,观察组患者各指标均明显优于参考组,P<0.05,观察组治疗中出现2例低血糖患者,参考组出现11例低血糖患者,两组比较有统计学意义,P<0.05。结论胰岛素与诺和平联合治疗2型糖尿病有助于控制血糖,低血糖发生率较低,值得推广使用。
Objective To investigate the clinical effect of insulin and Novolin in the treatment of type 2 diabetes. Methods Totally 90 patients with type 2 diabetes mellitus admitted to our hospital from January 2011 to January 2013 were randomly divided into observation group and reference group with 45 cases each. Patients in observation group were treated with combination therapy of insulin and Novolin. Patients in reference group Insulin injections were administered to observe the changes of blood glucose (PBG), fasting blood glucose (FBG), HbA1c and the incidence of hypoglycemia 2h after and before treatment in both groups. Results After treatment, the levels of PBG, FBG and HbA1c in both groups were significantly decreased. The indexes in the observation group were significantly better than those in the reference group, P <0.05. Two cases of hypoglycemia occurred in the observation group and 11 cases of hypoglycemia in the reference group Patients, the two groups were statistically significant, P <0.05. Conclusion The combination of insulin and Novolin in the treatment of type 2 diabetes helps to control blood sugar, the incidence of hypoglycemia is low, it is worth to promote the use.