[目的]探讨全直肠系膜切除术(TME)联合双吻合器技术(DST)在低位直肠癌手术中的效果。[方法]回顾性分析2005年6月至2010年6月应用TME联合DST治疗36例直肠癌患者的临床资料。[结果]全组术中直肠闭合切割和直肠—乙状结肠吻合过程均顺利。术后发生吻合口瘘2例(5.6%),吻合口出血1例(2.8%),伤口感染1例(2.8%),吻合口狭窄2例(5.6%)。全组无手术死亡。[结论]TME联合DST应用在低位直肠癌保肛术中是一种安全可靠的方法。 [Objective] To investigate the effect of total mesorectal excision (TME) combined with double stapling technique (DST) in low rectal cancer surgery. [Methods] The clinical data of 36 patients with rectal cancer treated with TME combined with DST from June 2005 to June 2010 were retrospectively analyzed. [Results] All the procedures of rectal closure and rectal-sigmoid colon anastomosis were successful. Anastomotic fistula occurred in 2 cases (5.6%), anastomotic bleeding in 1 case (2.8%), wound infection in 1 case (2.8%) and anastomotic stenosis in 2 cases (5.6%). The whole group died without surgery. [Conclusion] TME combined with DST is a safe and reliable method in anal sphincter preservation of low rectal cancer.