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目的在安慰剂对照的多中心临床试验中,通过减影方案与常规配对比较的无注册MR影像的比较,探索减影MRI在检测活动性多发硬化症(MS)病灶、直接定量分析病变的负荷变化以及检测治疗效果上的可应用性。方法 研
Objective To investigate the effect of subtraction MRI on the detection of active focal sclerosis (MS) lesions in a placebo-controlled, multicenter clinical trial by comparing the subtraction protocol with unpaired MR images of routinely matched pairs to directly quantify the lesion load Change and test the therapeutic effect on the applicability. Method research