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目的探讨急性脑梗死患者的动脉内区域性和接触性溶栓治疗。方法回顾分析本院150例急性脑梗死患者动脉内溶栓的临床资料。治疗时间为起病1～24h。DSA全脑血管造影,找到闭塞的责任血管。根据闭塞的血管的情况选择区域性动脉溶栓和超选择性动脉插管动脉内接触性溶栓,尿激酶以微量泵持续泵入,过程中经造影管或导引导管造影,了解闭塞血管再通情况。结果颈内动脉系统血管闭塞88例,血管再通57例。椎-基底动脉系统闭塞58例,血管再通38例。临床症状完全恢复及明显好转90例、占总病例60%,再次闭塞5例,脑出血5例,其中2例因脑疝死亡。结论神经介入动脉内溶栓是治疗急性脑梗死的一种有效治疗方法。
Objective To investigate intra-arterial regional and contact thrombolysis in patients with acute cerebral infarction. Methods The clinical data of intra-arterial thrombolysis in 150 patients with acute cerebral infarction in our hospital were retrospectively analyzed. The treatment time is onset 1 ~ 24h. DSA Cerebral angiography to find the vessel responsible for occlusion. According to the occlusion of the vessel to select the regional arterial thrombolysis and superselective arterial intrathecal intra-arterial thrombolysis, urokinase with a small pump continued to pump in the course of imaging tube or guide catheter angiography to understand the occlusion of blood vessels and then Pass situation. Results Internal carotid artery occlusion in 88 cases, 57 cases of recanalization. Vertebrobasilar artery occlusion in 58 cases, recanalization in 38 cases. Complete recovery of clinical symptoms and 90 cases of significant improvement, accounting for 60% of the total cases, occlusion in 5 cases again, 5 cases of cerebral hemorrhage, of which 2 cases died of cerebral hernia. Conclusion Intravenous arterial thrombolysis is an effective treatment for acute cerebral infarction.