[目的]调查泉州市莱姆病的病原、传播媒介、宿主动物及人群感染情况。[方法]以流行病学、血清学、病原学等方法调查泉州市部分地区人群感染以及鼠类、野兔及牛等动物体表的蜱类,用 PCR 法检测其伯氏疏螺旋体 DNA。 [结果]首次确认泉州市存在莱姆病病例,安溪、永春等县林区人群存在感染,从粒形硬蜱中检出伯氏疏螺旋体 DNA；从黄毛鼠、白腹巨鼠及野兔查出特异性抗体。[结论]从流行病学和病原学上证实泉州市存在莱姆病及其媒介与宿主, 是当地一种新发现的人兽共患传染病。 [Objective] To investigate the infection of Lyme disease, vectors, host animals and human in Quanzhou. [Methods] The epidemic, serological, etiological and other methods were used to investigate ticks in human body in some areas of Quanzhou, as well as rodent, hare and cow animals. The Borrelia burgdorferi DNA was detected by PCR. [Results] For the first time confirmed the presence of Lyme disease in Quanzhou, Anxi and Yongchun counties were infected with Borrelia burgdorferi DNA; A specific antibody. [Conclusion] It is epidemiologically and etiologically confirmed that Lyme disease, its vector and host exist in Quanzhou, which is a newly discovered zoonosis in Quanzhou.