论文部分内容阅读
本文通过30例高血压病患者用心得安治疗,于服药前后进行窦房结(SAN)功能测定,目的是探讨高血压患者用心得安治疗后对SAN功能的影响,以利安全用药。 一、病例选择及用药方法确诊为原发性高血压病者共30例,男18例,女12例,病程11.44±8.49年,用药前平均血压178.7±26.6/103.2±5.47mmHg。给予心得安20~30mg,3次/日,口服,14-21天为一疗程。用药前后均经食道心房调搏按常规做SAN功能测定。 二、结果 1. 心得安对高血压分期患者SAN功能的影响见表1。 Ⅱ期患者用心得安后SAN功能无明显变化,Ⅲ期患者用药后SNRT、SNRTc,SACT略延长,经统计学处理有差异,但属正常范围。 2.心得安治疗前后对血压的影响见表2。
In this paper, 30 cases of hypertensive patients with propranolol therapy, before and after taking the sino-atrial node (SAN) function test, the purpose is to explore the hypertensive patients with propranolol SAN effect on the treatment for the safe use of drugs. First, the choice of cases and methods of treatment diagnosed as essential hypertension in patients with a total of 30 cases, 18 males and 12 females, duration of 11.44 ± 8.99 years, the average blood pressure before treatment 178.7 ± 26.6 / 103.2 ± 5.47mmHg. Give peace of mind 20 ~ 30mg, 3 times / day, oral, 14-21 days for a course of treatment. Before and after treatment by esophageal atrial pacing according to conventional SAN function determination. Second, the results 1. Empathy on the staging of patients with hypertension SAN function in Table 1. There was no obvious change in SAN function in patients with stage II disease. SNRT, SNRTc and SACT were slightly prolonged after treatment in patients in stage III, but the difference was statistically significant but within the normal range. 2. Experience before and after treatment on the impact of blood pressure in Table 2.