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目的观察阿奇霉素序贯疗法治疗小儿支原体肺炎的临床效果。方法选择80例支原体肺炎患儿,随机分为常规组和治疗组,每组40例。常规组应用红霉素治疗,治疗组应用阿奇霉素序贯疗法治疗。观察2组临床疗效、不良反应发生情况及住院时间和临床症状、体征消失时间。结果治疗组总有效率为97.50%,高于常规组的77.50%,不良反应发生率低于常规组,住院时间及临床症状和体征消失时间短于常规组,差异均有统计学意义(P<0.05)。结论阿奇霉素序贯疗法治疗小儿支原体肺炎可提高治疗效果,缩短住院时间及临床症状和体征时间,减少不良反应。
Objective To observe the clinical effect of sequential treatment of azithromycin in children with mycoplasma pneumonia. Methods Eighty children with mycoplasma pneumonia were randomly divided into routine group and treatment group, 40 cases in each group. Routine group application of erythromycin treatment, the treatment group applied azithromycin sequential therapy. The clinical curative effect, the incidence of adverse reactions, the length of hospital stay, the clinical symptoms and signs disappeared were observed in the two groups. Results The total effective rate of the treatment group was 97.50%, higher than that of the conventional group (77.50%). The incidence of adverse reactions was lower than that of the conventional group, and the duration of hospitalization, clinical symptoms and signs disappeared shorter than that of the conventional group (P < 0.05). Conclusion Sequential azithromycin treatment of children with mycoplasma pneumonia can improve the therapeutic effect, shorten the hospital stay and clinical symptoms and signs of time, reduce adverse reactions.