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着重介绍造血干细胞移植治疗珠蛋白生成障碍性贫血时,患者的临床分度与预后的关系;供体的选择策略;移植采用的预处理和移植物抗宿主病的特点及预防。分析珠蛋白生成障碍性贫血的排斥机制,提出了克服排斥的新思路。
It focuses on the relationship between the clinical index and the prognosis of patients with hematopoietic stem cell transplantation for treatment of globin aplasia; the strategy of donor selection; the characteristics of pretreatment and graft-versus-host disease in transplantation and its prevention. Analysis of the rejection mechanism of globin aplastic anemia, put forward a new idea to overcome the exclusion.