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目的:比较各种炮制方法对关木通减毒存效作用,选择最佳的关木通炮制方法。方法:以关木通生品及各炮制品中马兜铃酸A、齐墩果酸及常春藤皂苷元含量为指标,比较了5种炮制方法(醋炙、蜜炙、姜炙、碱制、盐炙)减毒存效效果。结果:生品、醋炙品、蜜炙品、姜炙品、碱制品、盐炙品中马兜铃酸A含量分别为0.27%,0.13%,0.15%,0.20%,0.14%,0.18%;齐墩果酸含量分别为0.21%,0.15%,0.20%,0.13%,0.01%,0.01%;常春藤皂苷元含量分别为0.11%,0.08%,0.09%,0.07%,0.01%,0.01%。结论:关木通最佳减毒存效炮制方法为蜜炙法。
OBJECTIVE: To compare the effects of various methods of preparation on the attenuated drug-killing effect of Guan Mu Tong and choose the best method of Guan Mu Tong. Methods: The contents of aristolochic acid A, oleanolic acid and hederagenin were compared in five kinds of processing methods (vinegar, honey, ginger, sunburn, alkali, salt Sunburn) effect of reducing the effect of storage. Results: The contents of aristolochic acid A were 0.27%, 0.13%, 0.15%, 0.20%, 0.14% and 0.18% respectively in raw products, vinegar, sunbeam products, ginger sunburn products, The contents of oleanolic acid were 0.21%, 0.15%, 0.20%, 0.13%, 0.01% and 0.01%, respectively. The content of heliotropin was 0.11%, 0.08%, 0.09%, 0.07%, 0.01% and 0.01%, respectively. Conclusion: Guanmutong the best method for reducing the time-consuming processing method for honey Sunburn method.