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目的:探讨硫酸镁与小剂量阿司匹林联合治疗妊娠高血压疾病的临床疗效。方法:回顾性分析我院2014年2月至2016年2月期间收治的48例妊娠高血压患者的临床资料,将所有患者根据就诊顺序分为对照组和研究组,每组24例,对照组患者应用硫酸镁治疗,研究组患者在对照组的基础上联合应用小剂量阿司匹林治疗,比较两组患者治疗前后的血压变化及不良反应发生情况。结果:两组治疗后收缩压(SBP)及舒张压(DBP)较治疗前均有所下降,但研究组下降幅度显著优于对照组,两组比较差异有统计学意义(P<0.05),研究组患者治疗后不良反应发生率显著低于对照组,两组比较差异有统计学意义(P<0.05)。结论:硫酸镁与小剂量阿司匹林联合应用讷讷个有效的改善患者的高压,且不良反应少,值得临床进行应用推广。
Objective: To investigate the clinical efficacy of magnesium sulfate in combination with low-dose aspirin in the treatment of pregnancy-induced hypertension. Methods: The clinical data of 48 cases of pregnancy-induced hypertension in our hospital from February 2014 to February 2016 were retrospectively analyzed. All the patients were divided into control group and study group according to the order of treatment, with 24 cases in each group and control group Patients should be treated with magnesium sulfate. Patients in the study group were treated with low-dose aspirin on the basis of the control group. Changes in blood pressure and adverse reactions before and after treatment were compared between the two groups. Results: The systolic blood pressure (SBP) and diastolic blood pressure (DBP) decreased after treatment in both groups, but the reduction rate in the study group was significantly better than that in the control group. There was significant difference between the two groups (P <0.05) The incidence of adverse reactions in the study group was significantly lower than that in the control group after treatment, the difference between the two groups was statistically significant (P <0.05). Conclusion: Magnesium sulfate combined with low-dose aspirin can effectively improve the patient’s hypertension with less adverse reactions, which is worthy of clinical application.