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目的 探讨甲氨蝶呤 (MTX)和米非司酮联合治疗非破裂型输卵管妊娠的效果。方法 米非司酮30 0mg一次顿服 ,MTX2 0mg静注× 5d。单用MTX的病人设为对照组。 结果 MTX和米非司酮联合治疗的成功率为 87.5 % ,明显高于对照组。观察治疗期间病情变化 ,发现疗效与血 β -hCG高低及有无心管搏动有关。 结论 MTX和米非司酮联合治疗非破裂型输卵管妊娠安全有效 ,适用于生命体征平稳、无剧烈腹痛、无心管搏动及血 β -hCG <30 μg/L的非破裂型输卵管妊娠
Objective To investigate the effect of methotrexate (MTX) and mifepristone in the treatment of non-ruptured tubal pregnancy. Methods mifepristone 30 0mg a Dayton clothing, MTX2 0mg intravenously × 5d. MTX alone patients as a control group. Results The success rate of MTX combined with mifepristone treatment was 87.5%, which was significantly higher than that of the control group. Observe the changes of the course of treatment, found that the effect of blood β-hCG level and whether the cardiac tube beating related. Conclusion MTX combined with mifepristone in the treatment of non-ruptured tubal pregnancy is safe and effective. It is suitable for non-ruptured tubal pregnancy with stable vital signs, no severe abdominal pain, no cardiac tube beating and blood β -hCG <30 μg / L