心肌肥厚是影响心血管病预后的独立的危险因子。以往认为心肌肥厚是心脏对压力负荷增加的代偿性反应，近年来的研究表明心肌肥厚的发生和逆转不仅仅依赖于压力负荷的改变，许多体液因子包括组织局部的肾素－血管紧张素系统、一氧化氮（ＮＯ）、自由基等都可能参与了该过程... Cardiac hypertrophy is an independent risk factor that affects the prognosis of cardiovascular disease. In the past that cardiac hypertrophy is the heart of the stress response to the increase in stress response, recent studies have shown that the occurrence and reversal of cardiac hypertrophy depends not only on changes in stress load, and many humoral factors, including local tissue renin - angiotensin system , Nitric oxide (NO), free radicals, etc. may all participate in the process ...