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目的探讨急性有机磷农药中毒血清胆碱酯酶活性与临床中毒程度的关系。方法观察近2年来本院收治的急性有机磷农药中毒患者29例,用化学法检测血清胆碱酯酶活性,并分析其与临床中毒程度的关系。结果血清胆碱酯酶变化与临床中毒程度无明显相关。结论胆碱酯酶活性只能作为中毒诊断的参考指标,诊断分级应以临床表现为主要依据。
Objective To investigate the relationship between serum cholinesterase activity and clinical poisoning in patients with acute organophosphorus pesticide poisoning. Methods 29 cases of acute organophosphorus pesticide poisoning admitted to our hospital in the recent 2 years were observed. The serum cholinesterase activity was detected by chemical method and its relationship with the degree of clinical poisoning was analyzed. Results The change of serum cholinesterase had no significant correlation with clinical poisoning. Conclusion Cholinesterase activity can only serve as a reference index for the diagnosis of poisoning. The diagnosis and grading should be based on clinical manifestations.