目的探讨心肌肌钙蛋白Ⅰ对急性心肌梗死的临床意义。方法对73例急性心肌梗死患者测定cTnI和CK-MB,并且同时进行溶栓治疗,观察其动态变化。结果急性心肌梗死患者血清cTnI和CK-MB开始升高时间,高峰出现时间在溶栓再通者中有非常明显差异(P<0.01),急性心肌梗死患者入院72h后测定cTnI的特异性明显高于CK-MB(P<0.005)。结论监测cTnI比CK-MB对AMI患者更有意义。 Objective To investigate the clinical significance of cardiac troponin Ⅰ in acute myocardial infarction. Methods cTnI and CK-MB were measured in 73 patients with acute myocardial infarction. Thrombolysis was also performed and the dynamic changes were observed. Results The serum cTnI and CK-MB levels in patients with acute myocardial infarction began to increase, the peak time appeared in thrombolytic recanalization were significantly different (P <0.01), acute myocardial infarction patients measured 72h after cTnI specificity was significantly higher On CK-MB (P <0.005). Conclusion Monitoring cTnI is more meaningful than CK-MB in AMI patients.