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目的 :为了探讨一种新发现的肿瘤标志物DR 70对鼻咽癌是否有辅助诊断价值。方法 :采用ELISA法检测 6 2例鼻咽癌 (低分化鳞癌 )患者与 5 0例对照组血清中DR 70值。结果 :鼻咽癌组DR 70含量为 (7.40± 1.7)mg L ,阳性 2 6例 ,占42 % ,对照组 (4 .42± 2 .1)mg L ,阳性 3例 ,占 6 %。经检验 ,两组均数与阳性率之间差别有极显著性意义。结论 :DR 70在鼻咽癌病人血清中明显升高 ,对于鼻咽癌的辅助诊断有一定价值。
Objective: To investigate whether a newly discovered tumor marker, DR 70, has diagnostic value for nasopharyngeal carcinoma. Methods: Serum levels of DR 70 were detected by ELISA in 62 patients with nasopharyngeal carcinoma (poorly differentiated squamous cell carcinoma) and 50 controls. Results: The percentage of DR 70 in nasopharyngeal carcinoma was (7.40 ± 1.7) mg L, 26 cases were positive (42%) and 4 (42.4 ± 2.1) mg L in control group, accounting for 6%. After testing, the difference between the two groups and the positive rate has a very significant significance. Conclusion: The serum level of DR 70 is significantly elevated in patients with nasopharyngeal carcinoma, which is of value in the auxiliary diagnosis of nasopharyngeal carcinoma.